
As part of their training, fellows are required to participate in investigator-initiated clinical or translational research. The research requirement is flexible, enabling research-focused fellows the ability to develop a project from beginning to end as well as allowing more practice-focused fellows to gain research experiences as part of pre-existing projects. The goal of the research requirement is to develop critical thinking skills that are unique to scientific investigation and provide fellows a broader perspective to interpret scientific literature. Typically, fellows develop their research projects during the first year and have reduced responsibilities on the inpatient service and in outpatient clinics in year two to allow time for the completion of their projects.
Fellows are guided and supported in their projects by the research director, faculty mentors, research coordinators, and the resources of the MedStar Health Research Institute (MHRI). Dedicated lectures about research methodology, immunology, and statistical methods are part of the fellow curriculum. MHRI coordinates the research activities of all institutions within the MedStar Health system, providing infrastructure to support clinical research and supervises the animal laboratories on site. The Department of Medicine’s use of the Centricity and Amalga computerized medical record systems makes both inpatient and outpatient data amenable to clinical research studies.
For fellows interested in laboratory immunology of rheumatic diseases, there are active collaborations with Dr. Nagaraju Kanneboyina at the Children’s Research Institute at Children’s National Medical Center. The faculty also works with large population datasets such as the Women’s Health Initiative and the National Databank of Rheumatic Disease and has experience with meta-analysis, including the Cochrane Review. The rheumatology division has laboratory space in the Hyman Research Building and a freezer for specimen storage. The division has intramural and extramural funding to support its research activities. The Office of Graduate Medical Education also offers generous funding for IRB-approved trainee research projects which pays for statistical support, supplies, etc and the presentation of research at conferences or meetings.
RESEARCH PROJECTS
DIVISION OF RHEUMATOLOGY
Date: 09/06/12
|
PHARMACEUTICAL |
GRANT |
PHASE |
Presentation |
Publication |
|
STARA Trial [AW/FC/RN] |
2012 |
IRB |
|
|
|
Lymphostat B infusion for SLE, Phase II, III [AW/CC] |
2007 |
Extension (4) |
+ |
+ |
|
Anti-IL6 for SLE, Phase II [AW, CC, RN] |
2011 |
Enrolling |
- |
- |
|
ATLAS (anti-Tweak for SLE nephritis) [CC/TM] |
2012 |
IRB |
|
|
|
EMBRACE (Benlysta for SLE in AA) [CC/PB] |
2012 |
IRB |
|
|
|
Neurotropin for FM [BW, LS] |
2011 |
Recruiting Assistance |
- |
- |
|
OTHER FUNDED STUDIES |
|
|
|
|
|
SLE registry [AW/Chehab] |
2012 |
Protocol Design |
|
|
|
ENABLE (Belysta in clinical practice) |
2010 |
Complete/Expansion Planned |
+ |
- |
|
Evaluation of specific markers of rheumatoid arthritis, inflammation, thrombogenesis and risk of cardiovascular disease and total mortality: WHI [BW] |
2009-2011 |
Complete |
+ |
+ |
|
Correlates of axial gout [RK,AW, EL] |
2008 |
Severity Expansion Study Considered |
+ |
+ |
|
fMRI in FM, OA, Controls: Investigator Award [BW] |
2009-2012 |
Enrolling |
+ (2) |
- |
|
WHI ARD Coalition [BW, CC, FC] |
2010 |
Funded |
+ |
+ |
|
Fibromyalgia Evaluation and Research Center [BW] |
2010 |
Enrolling |
+ |
- |
|
EMRAC [RN] |
2011 |
Enrolling |
- |
- |
|
Vulvodynia and Fibromyalgia [BW/MB/JU] |
2012 |
Grant Submission |
|
|
|
Cardiovascular Stress Rehabilitation [SE/BW/JU] |
2012 |
Protocol Development |
|
|
|
OTHER STUDIES: Attending |
|
|
|
|
|
Racial steroid use health beliefs [FC, PK] |
2008 |
Complete |
+ |
- |
|
Cochrane Review: Fibromyalgia Meds [BW] |
2006 |
Manuscripts |
- |
+ (2) |
|
Anti-Mullerian Hormone in SLE [RN] |
2009 |
Negative Study |
- |
- |
|
Coffee consumption as predictor of ARD [CC, BW] |
2009 |
Manuscript |
+ |
- |
|
RA Focus Group Study [FC, JJ, LF] |
2009 |
On Hold |
- |
- |
|
Exertional exhaustion in GWI [JB, BW] |
2008 |
Complete |
- |
- |
|
Tinnitus and Fibromyalgia [BW] |
2012 |
Preliminary Data Generation |
|
|
|
Vitamin D in RA/SLE: WHI OS cohort |
2010 |
Complete |
+ |
- |
|
OTHER STUDIES: Fellow/Resident |
|
|
|
|
|
Spinal Cord Involvement in Lupus [NA/CM/RB/AW] |
2004 |
Enrolling |
+ |
- |
|
Isolated vs pan-complement Deficiency in SLE [AW/SD/JG/VD] |
2008 |
Completed |
+ |
- |
|
Amyloid Deposition in Fibromyalgia [DVN/BW] |
2012 |
Protocol Development |
|
|
|
Racial differences in Psoriatic Arthritis [GK, FC, IS] |
2008 |
Complete |
+ |
- |
|
RA symmetry [AW/BW] |
2005+ |
Analysis |
- |
- |
|
Ultrasound for sub-clinical gout in CHF [RN] |
2012 |
Protocol Development |
|
|
|
FMS Abuse Study [BW/WH] |
2012 |
IRB |
|
|