Gated perfusion imaging and MUGA

What is gated perfusion imaging?
Gated perfusion imaging evaluates motion of the heart muscle and how well the heart is pumping, which is measured as percent LVEF (left ventricular ejection fraction).  We perform this test at the same time as myocardial perfusion imaging, using a special computer program. 

By doing these tests at the same time, we are able to evaluate both blood flow and pumping function of the heart in one study and, in the majority of cases, in one visit.  Similar to the results of myocardial perfusion imaging, the results of the gated perfusion imaging also provides important information on prognosis and risk in patients with coronary artery disease.

What is MUGA (Multiple Gated Acquisition)?
MUGA evaluates motion of the heart muscle and pumping function of the heart. This test is ordered primarily in patients undergoing chemotherapy, to determine the presence and extent of side effect of chemotherapy on heart function.  Patients with heart failure or heart valve disease can also be evaluated with this study to determine the severity of the disease, based on its effect on the pumping function of the heart.

How does MUGA work?
MUGA (multiple gated acquisition) uses a radioactive tracer that attaches (or tags) to the red blood cells circulating through the heart.  Scans of the heart are also synchronized with the patient's EKG for evaluation of heart muscle motion and pumping function of the heart.

How do I prepare for gated perfusion imaging?

• Nothing to eat or drink after midnight, except for water or clear liquids for taking your medicines.
• If you are diabetic and take insulin or other medication for your diabetes, do not take your morning dose, but do bring your insulin or diabetes pills with you.  After your stress test, you will be allowed to have something to eat and you can take your diabetes medicine at that time.
• Absolutely no coffee, or other drinks and food that contain caffeine (including decaffeinated drinks), at least 12 hour before your study.
• No smoking at least 24 hours before the study.
• Wear comfortable clothing.  If you are scheduled to exercise on a treadmill exercise, also wear comfortable, rubber-soled shoes.
• Bring your doctor’s referral form for your study along with your medical insurance card.

Medications

• If you are on any prescription drugs for your heart and/or high blood pressure, ask your doctor if he wants you to continue taking, or stop taking, these medicines before your study.
• Bring a list of all your medications.

Precautions

• If there is a possibility that you are pregnant, or if you are breast-feeding, notify your doctor immediately, and notify the staff in Nuclear Medicine.

Learn more about what to expect before, during and after the test by visiting Patient Information: Nuclear Cardiology.